TRANSFORMING GROWTH-FACTOR RECEPTOR GENE TGFBR2 MAPS TO HUMAN-CHROMOSOME BAND 3P22

被引：45
|
作者：
MATHEW, S
MURTY, VVVS
CHEIFETZ, S
GEORGE, D
MASSAGUE, J
CHAGANTI, RSK
机构：
[1] MEM SLOAN KETTERING CANC CTR,DEPT PATHOL,NEW YORK,NY 10021
[2] MEM SLOAN KETTERING CANC CTR,HOWARD HUGHES MED INST,NEW YORK,NY 10021
来源：
GENOMICS | 1994年 / 20卷 / 01期
关键词：
D O I：
10.1006/geno.1994.1134
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In this study, we map the chromosomal position of the gene that encodes the type II receptor of TGF-beta (HGM symbol TGFBR2), a multifunctional regulator of cell proliferation and differentiation. Using a full-length cDNA and a genomic probe in Southern blot analysis of a human x rodent somatic cell hybrid panel and by direct fluorescence in situ hybridization to normal metaphase chromosomes, we show that the TGFBR2 gene maps to 3p22. (C) 1994 Academic Press, Inc.
引用
收藏
页码：114 / 115
页数：2
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