NUCLEAR SIGNALING BY INTERLEUKIN-6

被引：43
|
作者：
CHENKIANG, S
HSU, W
NATKUNAM, Y
ZHANG, XK
机构：
[1] Brookdale Center for Molecular Biology, Mount Sinai School of Medicine, New York, NY
来源：
CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 01期
关键词：
D O I：
10.1016/0952-7915(93)90091-6
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The molecular analysis of the regulation of nuclear proteins induced by interleukin-6 has provided new insights into this largely unknown signal transduction pathway. Transcription factors of the CCAAT/enhancer-binding protein and AP-1 families, as well as the octamer-binding proteins and the tumor suppressor gene product pRB, are regulated by interleukin-6 in a cell type specific manner, suggesting that they may play a role in the nuclear signaling by interleukin-6.
引用
收藏
页码：124 / 128
页数：5
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