DISSEMINATED CICATRICIAL PEMPHIGOID

The authors describe a typical case of a rare disease, disseminated cicatricial pemphigoid. At the site of the subepidermal bulla excessive scarring in seen. Electron microscopic examination reveals elastic fibrin deposition and incipient vacuolation under the basement membrane. The indirect immunoperoxidase study shows increased numbers of positive Langerhans cells, which support their antigen-presenting role.