FREE-RADICALS IN QUINONE-CONTAINING ANTITUMOR AGENTS - ELECTROCHEMICAL REDUCTION OF DIAZIQUONE (2,5-DIAZIRIDINE-3,6-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE) AND 2 ANALOGS

被引：0

作者：

GUTIERREZ, PL ^{[1
]}

FOX, BM ^{[1
]}

MOSSOBA, MM ^{[1
]}

BACHUR, NR ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,MED CHEM & PHARMACOL LAB,BETHESDA,MD 20205

来源：

MOLECULAR PHARMACOLOGY | 1984年 / 26卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：582 / 586

页数：5

共 21 条

[1] FREE-RADICALS IN QUINONE CONTAINING ANTI-TUMOR AGENTS - THE NATURE OF THE DIAZIQUONE (3,6-DIAZIRIDINYL-2,5-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE) FREE-RADICAL
GUTIERREZ, PL
BACHUR, NR
BIOCHIMICA ET BIOPHYSICA ACTA, 1983, 758 (01) : 37 - 41
[2] CELLULAR ACTIVATION OF DIAZIQUONE [2,5-DIAZIRIDINYL-3,6-BIS (CARBOETHOXYAMINO)-1,4-BENZOQUINONE] TO ITS FREE-RADICAL SPECIES
GUTIERREZ, PL
EGORIN, MJ
FOX, BM
FRIEDMAN, R
BACHUR, NR
BIOCHEMICAL PHARMACOLOGY, 1985, 34 (09) : 1449 - 1455
[3] 2,5-DIAZIRIDINYL-3,6-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE .2. ISOLATION AND CHARACTERIZATION OF DEGRADATION PRODUCTS
POOCHIKIAN, GK
KELLEY, JA
JOURNAL OF PHARMACEUTICAL SCIENCES, 1981, 70 (02) : 162 - 167
[4] MITOCHONDRIAL TOXICITY OF 2,5-DIAZIRIDINYL-3,6-BIS-(CARBOETHOXYAMINO)-1,4-BENZOQUINONE
OBERCGREENWOOD, MA
SMITH, BH
COOKE, C
ELLIS, JR
KORNBLITH, PL
MCKEEVER, PE
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1983, 71 (04) : 723 - 733
[5] COMPARISON OF THE STRUCTURAL AND CYTOTOXIC ACTIVITY OF NOVEL 2,5-BIS(CARBOETHOXYAMINO)-3,6-DIAZIRIDINYL-1,4-BENZOQUINONE ANALOGS
DZIELENDZIAK, A
BUTLER, J
HOEY, BM
LEA, JS
WARD, TH
CANCER RESEARCH, 1990, 50 (07) : 2003 - 2008
[6] PHASE-II AND PHARMACOKINETIC STUDY OF AZIRIDINYLBENZOQUINONE [2,5-DIAZIRIDINYL-3,6-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE, DIAZIQUONE, NSC-182986] IN HIGH-GRADE GLIOMAS
CURT, GA
KELLEY, JA
KUFTA, CV
SMITH, BH
KORNBLITH, PL
YOUNG, RC
COLLINS, JM
CANCER RESEARCH, 1983, 43 (12) : 6102 - 6105
[7] QUANTITATIVE-DETERMINATION OF 2,5-DIZIRIDINYL-3,6-BIS(CARBOETHOXYAMINO-1,4-BENZOQUINONE) AND ITS DEGRADATION PRODUCTS BY PMR SPECTROSCOPY
MOHAMED, ZH
SPECTROSCOPY LETTERS, 1987, 20 (6-7) : 565 - 573
[8] 2,5-DIAZIRIDINYL-3,6-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE .1. KINETICS IN AQUEOUS-SOLUTIONS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
POOCHIKIAN, GK
CRADOCK, JC
JOURNAL OF PHARMACEUTICAL SCIENCES, 1981, 70 (02) : 159 - 162
[9] INDUCTION OF DNA STRAND BREAKS AND CROSS-LINKS BY 2,5-DIAZIRIDINYL-3,6-BIS(CARBOETHOXYAMINO)-1,4-BENZOQUINONE IN CHINESE-HAMSTER OVARY CELLS
KING, CL
HITTELMAN, WN
LOO, TL
CANCER RESEARCH, 1984, 44 (12) : 5634 - 5637
[10] A PHASE-II TRIAL OF 2,5-DIAZIRIDINYL3,6-BIS(CARBOETHOXYAMINO)1,4-BENZOQUINONE(AZQ,NSC-182986) IN RECURRENT PRIMARY BRAIN-TUMORS
FEUN, LG
YUNG, WKA
LEAVENS, ME
BURGESS, MA
OBBENS, EA
BEDIKIAN, AY
SAVARAJ, N
STEWART, DJ
BENJAMIN, RS
FIELDS, WS
BODEY, GP
JOURNAL OF NEURO-ONCOLOGY, 1984, 2 (01) : 13 - 17

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