CHEMISTRY RELEVANT TO THE BIOLOGICAL EFFECTS OF NITRIC-OXIDE AND METALLONITROSYLS

被引：98
|
作者：
CLARKE, MJ
GAUL, JB
机构：
来源：
STRUCTURE AND BONDING | 1993年 / 81卷
关键词：
D O I：
10.1007/BFb0036819
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Nitric oxide has recently been found to be important messenger molecule mediating critical physiological functions such as neurotransmission and muscle relaxation. The nitroprusside ion, which is clinically used as a vasodilator, functions by releasing NO in vivo. The reactivities of these molecules are surveyed with a view toward the development of metallonitrosyls as pharmaceutical agents.
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页码：147 / 181
页数：35
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