AUTOMATED SOLID-PHASE SYNTHESIS OF CYCLIC OLIGONUCLEOTIDES - A FURTHER IMPROVEMENT

被引：23

作者：

DENAPOLI, L

GALEONE, A

MAYOL, L

MESSERE, A

MONTESARCHIO, D

PICCIALLI, G

机构：

[1] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM ORGAN & BIOL,I-80134 NAPLES,ITALY

[2] UNIV NAPLES FEDERICO II,DIPARTIMENTO CHIM SOSTANZE NAT,I-80131 NAPLES,ITALY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1995年 / 3卷 / 10期

关键词：

D O I：

10.1016/0968-0896(95)00090-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solid phase approach for the preparation of cyclic oligodeoxy- and oligo-rebonucleotides was improved thus allowing the fully automated synthesis of larger DNA and RNA circles, using commercially available amidite building blocks.

引用

页码：1325 / 1329

页数：5

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