Rapidly Evolving Giant Dermatofibroma

被引:5
|
作者
Lang, K. J. [1 ]
Lidder, S. [2 ]
Hofer, M. [3 ]
Graham, C. [3 ]
Taylor, A. [1 ]
机构
[1] Stoke Mandeville Hosp, Dept Gen Surg, Mandeville Rd, Aylesbury HP21 8AL, Bucks, England
[2] Stoke Mandeville Hosp, Dept Plast Surg, Aylesbury HP21 8AL, Bucks, England
[3] Stoke Mandeville Hosp, Dept Histopathol, Aylesbury HP21 8AL, Bucks, England
关键词
D O I
10.1155/2010/620910
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Dermatofibroma, also known as "fibrous histiocytoma", is a benign dermal or subcutaneous poorly circumscribed proliferation of spindle-shaped fibroblasts and macrophages in the dermis. Although it is commonly present as a brownish nodule the legs of females, it may also arise on the upper extremities, trunk, and rarely on the head. The exact pathogenesis is unclear. However, it is widely believed that the originating insult to the dermis is a folliculitis, an arthropod bite, or an unspecified initial inflammatory condition. Giant dermatofibromas of greater than 5 cm in diameter are rare, with only 22 cases reported in the literature. We present a case of a rapidly evolving pedunculated mass in the groin of a male patient. Histological examination confirmed this to be a giant dermatofibroma. Though this specimen cannot is not confirmed as such, the cellular subtype is sometimes present as a larger lesion with anecdotal reports of local recurrence and distant metastases. The clinical and radiological features which were somewhat suspicious of malignancy are considered in the context of the definitive pathological diagnosis of a benign lesion.
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Rapidly Evolving Giant Coronary Aneurysm
    Bhindi, Ravinay
    Testa, Luca
    Ormerod, Oliver J.
    Banning, Adrian P.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (04) : 372 - 372
  • [2] GIANT DERMATOFIBROMA
    REQUENA, L
    FARINA, MC
    FUENTE, C
    PIQUE, E
    OLIVARES, M
    MARTIN, L
    SANCHEZ, E
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 30 (05) : 714 - 718
  • [3] Giant Hemosiderotic Dermatofibroma: The Largest Giant Dermatofibroma Reported to Date
    Kalsi, Herman
    Rahman, Anishur
    Harbol, Tracy
    Sidhu, Jagmohan
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2015, 37 (10) : 778 - 782
  • [4] Giant combined dermatofibroma
    Numajiri, T
    Kishimoto, S
    Shibagaki, R
    Kuramoto, N
    Takenaka, H
    Yasuno, H
    BRITISH JOURNAL OF DERMATOLOGY, 2000, 143 (03) : 655 - 657
  • [5] Giant dermatofibroma of the leg
    Akkari, H.
    Korbi, M.
    Njima, M.
    Belkahla, M.
    Zakhama, A.
    Belhadjali, H.
    Zili, J.
    ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 2017, 144 (6-7): : 466 - 467
  • [6] Giant Ulcerative Dermatofibroma
    Karlidag, Turgut
    Keles, Erol
    Orhan, Israfil
    Kaplama, Mehmet Erkan
    Cobanoglu, Bengu
    CASE REPORTS IN OTOLARYNGOLOGY, 2013, 2013
  • [7] Giant dermatofibroma with monster cells
    Goodman, WT
    Bang, RH
    Padilla, RS
    AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2002, 24 (01) : 36 - 38
  • [8] Giant combined dermatofibroma with satellitosis
    Sehgal, VN
    Sardana, K
    Khandpur, S
    Sharma, S
    Majumdar, S
    Aggarwal, AK
    CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2004, 29 (02) : 147 - 149
  • [9] Giant dermatofibroma: a rare variant of dermatofibroma preferentially developing on the lower limbs
    Hoshina, D.
    Shibaki, A.
    Aoyagi, S.
    Kimura, K.
    Shimizu, H.
    CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2007, 32 (01) : 132 - 134
  • [10] Giant dermatofibroma appearing during pregnancy
    Micantonio, T
    Fargnoli, MC
    Peris, K
    ACTA DERMATO-VENEREOLOGICA, 2006, 86 (01) : 86 - 87