The Bucaramanga Segment (BS) of the Bucaramanga Faults System (BFS), located among the municipalities of Pailitas and Curumam, Department of Cesar, Colombia, has been interpreted as a reverse type fault of high angle, with the East Block up-lifted. By means of structural and microstructural analysis of the units outcropping, the behavior of this fault segment is established for this sector, as well as its relationship with the surrounding structures. The obtained results indicate that the BS presents a NNW direction with left lateral component and a strong shear zone of about 5 km wide, in which ductile (mylonites) and brittle (cataclasites) fault rocks are present. The occurrence of pseudotachylites in the BS suggests frictional slip faults, probably with seismic events associated. Additionally, it was found that the BFS is superimposed by two major phases of deformation, the first is related to low-angle thrust faults with tectonic transport to the West and the second, comprises NE-SW right lateral faults, related to a Espiritu Santo Fault's left branching splay.