Dual-stage F-18-fluorocholine PET/CT scanning for biochemical recurrences of prostate cancer

被引：2

作者：

Dolgushin, M. B. ^{[1
]}

Odzharova, A. A. ^{[1
]}

Mikhailov, A. I. ^{[1
]}

Shiryaev, S. V. ^{[2
]}

Tulin, P. E. ^{[1
]}

Nevzorov, D. I. ^{[1
]}

Matveev, V. B. ^{[3
]}

机构：

[1] NN Blokhin Russian Canc Res Ctr, Dept Positron Emiss Tomog, 23 Kashirskoe Shosse, Moscow 115478, Russia

[2] NN Blokhin Russian Canc Res Ctr, Dept Radionuclide Diag & Radionuclide Therapy, Moscow 115478, Russia

[3] NN Blokhin Russian Canc Res Ctr, Urol Dept, Moscow 115478, Russia

来源：

ONKOUROLOGIYA | 2015年 / 11卷 / 02期

关键词：

PET/CT; two-staged; prostate cancer; F-18-fluorocholine; choline; biochemical recurrence; prostatectomy;

D O I：

10.17650/1726-9776-2015-11-2-46-54

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

PET/CT with F-18-fluorocholine, based on an assessment of phosphatidylcholine biodistribution, is an effective method in the diagnosis of biochemical recurrence of prostate cancer. According to results of our study on 71 patients (PSA level 1,775 (0.0245, 56.0975) ng/mL), the sensitivity of two-stage PET/CT with F-18-fluorocholine was 66.7% (CI55.3-78 0 %), and specificity - 80 % ( CI 44.9-100.0 %), the overall accuracy of the method ranged from 56.7 to 78.5 %. The results show the feasibility of two-staged PET/CT with 18F-fluorocholine in biochemical recurrence of prostate cancer.

引用

页码：46 / 54

页数：9

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