A SYSTEMATIC EVALUATION OF THE INHIBITION OF HIV-1 PROTEASE BY ITS C-TERMINAL AND N-TERMINAL PEPTIDES

被引：31
|
作者：
FRANCISKOVICH, J
HOUSEMAN, K
MUELLER, R
CHMIELEWSKI, J
机构：
[1] PURDUE UNIV, DEPT CHEM, W LAFAYETTE, IN 47907 USA
[2] SEARLE RES & DEV, SKOKIE, IL 60022 USA
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 04期
关键词：
D O I：
10.1016/S0960-894X(01)81271-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
C- and N-terminal peptides of varying lengths corresponding to the dimerization interface of the retroviral protease of the human immunodeficiency virus-1 (HIV-1 protease) have been synthesized and evaluated as inhibitors of HIV-1 protease activity.
引用
收藏
页码：765 / 768
页数：4
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