Non-Muscle-Invasive Bladder Cancer in the Elderly Patient

被引:0
|
作者
Hofbauer, Sebastian L. [1 ]
Shariat, Shahrokh F. [1 ,2 ]
Klatte, Tobias [1 ]
机构
[1] Med Univ Vienna, Vienna Gen Hosp, Dept Urol, Wahringer Gurtel 18-20, A-1090 Vienna, Austria
[2] New York Presbyterian Hosp, Weill Cornell Med Coll, Dept Urol, New York, NY USA
关键词
Age; Elderly; Non-muscle-invasive; Bladder cancer; Immunotherapy; Bacillus Calmette-Guerin; Chemotherapy; Incidence; Prognosis; Recurrence; Progression;
D O I
10.1007/s13670-013-0071-4
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
With increasing life expectancy, both the incidence and the prevalence of bladder cancer (BC) are steadily rising. As over 70 % of newly diagnosed cases are non-muscleinvasive BC (NMIBC), the management of this entity plays a growing role. Clinical decision-making obviously involves age as an essential variable, but there are no evidence-based recommendations for healthcare professionals that stratify diagnosis, staging or therapy based on age. Data suggest that elderly patients are more frequently diagnosed with high stage and high grade NMIBC, and have worse recurrence and progression rates than younger patients. Moreover, elderly patients face both clinical and institutional barriers to appropriate evidence- based treatment; i.e. they are less likely to undergo re-resections, intravesical instillations and early radical cystectomy. Careful patient selection, and treatment algorithms tailored to the needs and the physiological and physical reserve of the individual patient are particularly important. Interdisciplinary collaborative efforts should focus to provide tailored geriatric care for all elderly patients with NMIBC.
引用
收藏
页码:42 / 47
页数:6
相关论文
共 50 条
  • [1] Non-Muscle-Invasive Bladder Cancer in the Elderly Patient
    Sebastian L. Hofbauer
    Shahrokh F. Shariat
    Tobias Klatte
    [J]. Current Geriatrics Reports, 2014, 3 (1): : 42 - 47
  • [2] Landmarks in non-muscle-invasive bladder cancer
    Laura S. Mertens
    Yann Neuzillet
    Simon Horenblas
    Bas W. G. van Rhijn
    [J]. Nature Reviews Urology, 2014, 11 : 476 - 480
  • [3] Approaches to Non-Muscle-Invasive Bladder Cancer
    Hannah Slovacek
    Jerry Zhuo
    Jennifer M. Taylor
    [J]. Current Oncology Reports, 2021, 23
  • [4] Approaches to Non-Muscle-Invasive Bladder Cancer
    Slovacek, Hannah
    Zhuo, Jerry
    Taylor, Jennifer M.
    [J]. CURRENT ONCOLOGY REPORTS, 2021, 23 (09)
  • [5] Study on non-muscle-invasive Bladder Cancer Therapy
    Rexer, H.
    [J]. UROLOGE, 2016, 55 (04): : 528 - 531
  • [6] Diagnosis and treatment of non-muscle-invasive bladder cancer
    Mostafid, Hugh
    Bryan, Richard T.
    Rees, Jonathan
    [J]. TRENDS IN UROLOGY & MENS HEALTH, 2015, 6 (02) : 23 - +
  • [7] TIMELINE Landmarks in non-muscle-invasive bladder cancer
    Mertens, Laura S.
    Neuzillet, Yann
    Horenblas, Simon
    van Rhijn, Bas W. G.
    [J]. NATURE REVIEWS UROLOGY, 2014, 11 (08) : 476 - 480
  • [8] Novel cryotherapy in non-muscle-invasive bladder cancer
    Ho, Matthew D.
    Modi, Parth K.
    [J]. CANCER, 2023, 129 (03) : 333 - 334
  • [9] Photodynamic Diagnosis in Non-Muscle-Invasive Bladder Cancer
    Bordier, Benoit
    Mazerolles, Catherine
    Malavaud, Bernard
    [J]. EUROPEAN UROLOGY SUPPLEMENTS, 2010, 9 (03) : 411 - 418
  • [10] New therapies for non-muscle-invasive bladder cancer
    Edmund Chiong
    Kesavan Esuvaranathan
    [J]. World Journal of Urology, 2010, 28 : 71 - 78