RESPONSE TO CHOLESTEROL-LOWERING DRUGS IN FAMILIAL DEFECTIVE APOLIPOPROTEIN-B-100

被引：23
|
作者：
MAHER, VMG
GALLAGHER, JJ
THOMPSON, GR
MYANT, NB
机构：
[1] MRC Lipoprotein Team, Hammersmith Hospital, London
来源：
ATHEROSCLEROSIS | 1991年 / 91卷 / 1-2期
关键词：
FAMILIAL DEFECTIVE APOLIPOPROTEIN-B-100; CHOLESTEROL-LOWERING DRUGS;
D O I：
10.1016/0021-9150(91)90188-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The effect of cholestyramine and simvastatin, given separately or in combination, on serum lipid concentrations in 11 patients with heterozygous familial defective apolipoprotein B-100 was compared with that in 11 matched patients with heterozygous familial hypercholesterolaemia. In both groups of patients there was a substantial fall in serum lipid levels in response to treatment. There were no significant differences between the reductions in serum total or low-density lipoprotein cholesterol levels in the two groups.
引用
收藏
页码：73 / 76
页数：4
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