ESR EVIDENCE FOR THE OXIDATIVE CLEAVAGE OF GENTISIC ACID IN BASIC AQUEOUS-SOLUTION

被引：2

作者：

CAPELLE, S ^{[1
]}

PAILLAT, C ^{[1
]}

COTELLE, P ^{[1
]}

PLANCKAERT, B ^{[1
]}

CATTEAU, JP ^{[1
]}

机构：

[1] UST LILLE,CHIM PHYS ORGAN LAB,CNRS,URA 351,VILLENEUVE DASCQ,FRANCE

来源：

REDOX REPORT | 1995年 / 1卷 / 03期

关键词：

D O I：

10.1080/13510002.1995.11746988

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The oxidative cleavage of 2,5-dihydroxybenzoic acid (gentisic acid), presumably into maleylpyruvate in basic aqueous solution has been shown by ESR spectra of semiquinonic radicals bearing a methylenic group. One of these radicals has been unambiguously attributed to 2,4,5-trihydroxyphenylacetic acid semiquinonic radical. The formation of an hydroxylated homogentisic acid from gentisic acid (a metabolite of aspirin) is of particular importance in the treatment of alkaptonuria and related inflammatory arthritis.

引用

页码：219 / 223

页数：5

共 50 条

[1] THE CLEAVAGE OF ASPIRIN BY ALPHA-CYCLODEXTRINS AND BETA-CYCLODEXTRINS IN BASIC AQUEOUS-SOLUTION
TEE, OS
TAKASAKI, BK
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1985, 63 (12): : 3540 - 3544
[2] AGGREGATION OF PERFLUORINATED POLYMERS IN AQUEOUS-SOLUTION STUDIED BY ESR
MARTINI, G
OTTAVIANI, MF
RISTORI, S
LENTI, D
SANGUINETI, A
COLLOIDS AND SURFACES, 1990, 45 : 177 - 184
[3] ESR STUDIES OF PHOTOGENERATED NITROBENZYL CARBANIONS IN AQUEOUS-SOLUTION
MURALIDHARAN, S
WAN, P
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1991, 57 (1-3) : 191 - 206
[4] THE CLEAVAGE OF 1-NAPHTHYL AND 2-NAPHTHYL ACETATES BY CYCLODEXTRINS IN BASIC AQUEOUS-SOLUTION
TEE, OS
BOYD, MJ
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1995, (06): : 1237 - 1243
[5] THE KINETICS OF BASIC CLEAVAGE OF NITROPHENYL ALKANOATE ESTERS BY HYDROXYPROPYL-BETA-CYCLODEXTRIN IN AQUEOUS-SOLUTION
GADOSY, TA
TEE, OS
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1994, (04): : 715 - 721
[6] NATURE OF VANADIUM (4) IN BASIC AQUEOUS-SOLUTION
IANNUZZI, MM
RIEGER, PH
INORGANIC CHEMISTRY, 1975, 14 (12) : 2895 - 2899
[7] KINETICS OF PROTOLYSIS OF CRYPTANDS IN BASIC AQUEOUS-SOLUTION
COX, BG
KNOP, D
SCHNEIDER, H
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1978, 100 (19) : 6002 - 6007
[8] STATE OF BASIC ORGANIC DYES IN AQUEOUS-SOLUTION
ZADOROZH.EM
NABIVANE.BI
MASLEI, NN
ZHURNAL ANALITICHESKOI KHIMII, 1974, 29 (05): : 993 - 997
[9] OXIDATIVE CLEAVAGE OF AROMATIC AZINES WITH PERIODIC ACID - ESR EVIDENCE FOR LIBERATION OF NITROGEN DIOXIDE
FATIADI, AJ
CHEMISTRY & INDUSTRY, 1971, (02) : 64 - &
[10] INFLUENCE OF ACID-BASIC PROPERTIES OF ROCKS ON A COMPOSITION OF THE EQUILIBRATED AQUEOUS-SOLUTION
BORISOV, MV
RYZHENKO, BN
KRAYNOV, SR
GEOKHIMIYA, 1984, (05): : 705 - 713

← 1 2 3 4 5 →