According to Polish Society of Menopause and Andropause, andropause is a period of man's life following appearance of - progressing with age - deficiency of androgenic hormones, testosterone and dehydroepiandrosterone as well as growth hormone and melatonin, phenomena that usually develop after 50th year of age. Symptomatology of these changes is characterized by gradual deterioration of the quality of life, general physical and mental condition, work skills, libido and sexual functions' disorders, deterioration of intellectual competence and sleep disorders. The objective of this article is presentation pathophysiology of the period, considering clinical and laboratory diagnostics, treatment as well as myths related to andropause.