FETAL AND MATERNAL LEVELS OF CORTICOSTERONE AND ACTH AFTER PHARMACOLOGICAL ADRENALECTOMY

被引：25
|
作者：
BARAM, TZ
SCHULTZ, L
机构：
[1] Dept. Neurology, University of Southern California
来源：
LIFE SCIENCES | 1990年 / 47卷 / 06期
关键词：
D O I：
10.1016/0024-3205(90)90607-S
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
A paradigm of pharmacological adrenalectomy of pregnant rats and fetuses in utero is described. A regimen of twice daily metyrapone injections (10mg/100gm body weight), results in marked depression of serum corticosterone in pregnant and in fetal rats without surgical trauma and stress. The technique should be useful in a wide variety of studies involving the developing brain-adrenal axis. © 1990.
引用
收藏
页码：485 / 489
页数：5
相关论文
共 50 条
  • [1] FETAL-MATERNAL ADRENOCORTICOTROPIN AND CORTICOSTERONE RELATIONSHIPS IN THE RAT - EFFECTS OF MATERNAL ADRENALECTOMY
    CHATELAIN, A
    DUPOUY, JP
    ALLAUME, P
    [J]. ENDOCRINOLOGY, 1980, 106 (04) : 1297 - 1303
  • [2] EFFECT OF MATERNAL ADRENALECTOMY ON PITUITARY ACTH CELLS OF FETAL AND NEONATAL RATS
    HRISTIC, M
    PANTIC, V
    NICKERSON, P
    [J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 1978, 34 (01) : 75 - 75
  • [3] INFLUENCE OF MATERNAL ADRENALECTOMY ON PITUITARY ACTH-CELLS OF FETAL AND NEONATAL RATS
    HRISTIC, M
    PANTIC, V
    NICKERSON, PA
    [J]. ACTA VETERINARIA-BEOGRAD, 1978, 28 (06): : 231 - 241
  • [4] THE EFFECTS OF CAFFEINE AND CORTICOSTERONE ON MATERNAL PLASMA AND FETAL LEVELS OF CORTICOSTERONE IN PREGNANT MICE
    ELMAZAR, MMA
    SHOKRY, IM
    [J]. TERATOLOGY, 1984, 29 (03) : A22 - A23
  • [5] FETAL ADRENAL GROWTH AND FUNCTION AFTER MATERNAL ADRENALECTOMY
    JACKSON, BT
    RAUSCHEC.HF
    MALT, RA
    PIASECKI, GJ
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1970, 49 (06): : A47 - &
  • [6] MATERNAL AND FETAL CORTICOSTERONE LEVELS DURING LATE PREGNANCY IN RATS
    DUPOUY, JP
    COFFIGNY, H
    MAGRE, S
    [J]. JOURNAL OF ENDOCRINOLOGY, 1975, 65 (03) : 347 - 352
  • [7] ACTH LEVELS IN MATERNAL, FETAL AND NEONATAL PLASMA AFTER SHORT-TERM PRENATAL DEXAMETHASONE THERAPY
    KAUPPILA, A
    SIMILA, S
    YLIKORKALA, O
    KOIVISTO, M
    MAKELA, P
    HAAPALAHTI, J
    [J]. BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1977, 84 (02): : 124 - 128
  • [8] CORTICOSTERONE SECRETION BY RATS AFTER ADRENALECTOMY
    DAMASCO, MC
    DEPEDRAZZINI, MEJC
    [J]. ACTA PHYSIOLOGICA ET PHARMACOLOGICA LATINOAMERICANA, 1985, 35 (04): : 415 - 417
  • [9] EFFECT OF ADRENALECTOMY AT DIFFERENT PREGNANCY STAGES ON MATERNAL AND FETAL SERUM CORTICOSTEROID BINDING GLOBULIN AND CORTICOSTERONE IN THE RAT
    COHEN, A
    SAVU, L
    VRANCKX, R
    MAYA, M
    NUNEZ, EA
    [J]. ACTA ENDOCRINOLOGICA, 1990, 122 (01): : 121 - 126
  • [10] Effect of maternal adrenalectomy and corticosterone therapy on the early development of B-cells in the fetal pancreatic islet in the rat
    Komatsu, S
    Yamamoto, M
    Takizawa, T
    Shirai, M
    Arishima, K
    Eguchi, Y
    [J]. JOURNAL OF VETERINARY MEDICAL SCIENCE, 1996, 58 (10): : 995 - 999
12345