MUTAGENICITY OF BETA-GLUCURONIDASE IN THE AMES TEST

被引：3
|
作者：
CERNA, M
机构：
来源：
MUTATION RESEARCH | 1985年 / 143卷 / 03期
关键词：
D O I：
10.1016/S0165-7992(85)80030-0
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
The enzyme preparation .beta.-glucuronidase/arylsulfatase [.beta.-G] from Helix pomatia (Boehringer) caused base-pair substitutions in Salmonella typhimurium TA100 and TA1535 strains within the dose range of 0.50-50 .mu.l/plate. No effect was observed in the TA98 strain. The presence of S9 mix did not substantially affect the mutagenic potential of .beta.-G. The number of induced revertants decreased continually from experiment to experiment carried out in the course of 12 wk.
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页码：169 / 172
页数：4
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