Production and initial evaluation of a humanized BsF(ab')(2) anti-CD3-based bispecific monoclonal antibody designed for therapy of human B-cell malignancies.

被引：0
|
作者：
Link, BK
Moes, R
Fusselman, WP
Kostelny, SA
Cole, MS
Tso, JY
Weiner, GJ
机构：
[1] UNIV IOWA,IOWA CITY,IA
[2] PROT DESIGN LABS,MT VIEW,CA
来源：
BLOOD | 1995年 / 86卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1264 / 1264
页数：1
相关论文
共 50 条
  • [1] ANTI-CD3-BASED BISPECIFIC ANTIBODY THERAPY INDUCES RAPID REGRESSION OF ESTABLISHED B-CELL LYMPHOMA
    WEINER, G
    HILLSTROM, JR
    BELANI, R
    CLINICAL RESEARCH, 1994, 42 (03): : A423 - A423
  • [2] Preclinical evaluation of a humanized anti-CD74 monoclonal antibody hLL1, for treatment of B-cell malignancies.
    Stein, R
    Burton, JD
    Cardillo, TM
    Qu, ZX
    Ely, SA
    Reddy, P
    Chen, S
    Rosario, A
    Horak, ID
    Hansen, HJ
    Goldenberg, DM
    BLOOD, 2003, 102 (11) : 181A - 181A
  • [3] Anti-CD3-based bispecific antibody designed for therapy of human B-cell malignancy can induce T-cell activation by antigen-dependent and antigen-independent mechanisms
    Link, BK
    Kostelny, SA
    Cole, MS
    Fusselman, WP
    Tso, JY
    Weiner, GJ
    INTERNATIONAL JOURNAL OF CANCER, 1998, 77 (02) : 251 - 256
  • [4] T cell-dependent bispecific antibody anti-CD79b/CD3 as a potential therapy for B-cell malignancies
    Wang, Peiyin
    Hristopoulos, Maria
    Clark, Robyn
    Chen, Yvonne
    Ellerman, Diego
    Mathieu, Mary
    Spiess, Christoph
    Li, Jessica
    Chalouni, Cecile
    Sukumaran, Siddharth
    Stefanich, Eric
    Wallin, Jeffrey
    Li, Robert
    Zabka, Tanja
    Totpal, Klara
    Dennis, Mark
    Ebens, Allen
    Gould, Stephen
    Polson, Andrew
    Sun, Liping Laura
    CANCER RESEARCH, 2017, 77
  • [5] Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies
    Stein, R
    Qu, ZX
    Cardillo, TM
    Chen, S
    Rosario, A
    Horak, ID
    Hansen, HJ
    Goldenberg, DM
    BLOOD, 2004, 104 (12) : 3705 - 3711
  • [6] BISPECIFIC ANTIIDIOTYPE ANTI-CD3 ANTIBODY THERAPY OF MURINE B-CELL LYMPHOMA
    WEINER, GJ
    HILLSTROM, JR
    JOURNAL OF IMMUNOLOGY, 1991, 147 (11): : 4035 - 4044
  • [7] Characterization of anti-CD79b/CD3 bispecific antibody, a potential therapy for B cell malignancies
    Wang, Jie
    Li, Chen
    He, Kaijie
    Kuang, Zhihui
    Lu, Jia
    Yao, Ying
    He, Fufan
    Li, Ninghuan
    Li, Li
    Fu, Fenggen
    Wu, Zhihai
    Zhou, Shuaixiang
    Kang, Dian
    Qiu, Xuan
    Wu, Min
    Liu, Yang
    Cao, Xiaochao
    Xu, Mengqiu
    Chen, Bingliang
    Wu, Weiwei
    Guo, Feng
    CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023, 72 (02) : 493 - 507
  • [8] Characterization of anti-CD79b/CD3 bispecific antibody, a potential therapy for B cell malignancies
    Jie Wang
    Chen Li
    Kaijie He
    Zhihui Kuang
    Jia Lu
    Ying Yao
    Fufan He
    Ninghuan Li
    Li Li
    Fenggen Fu
    Zhihai Wu
    Shuaixiang Zhou
    Dian Kang
    Xuan Qiu
    Min Wu
    Yang Liu
    Xiaochao Cao
    Mengqiu Xu
    Bingliang Chen
    Weiwei Wu
    Feng Guo
    Cancer Immunology, Immunotherapy, 2023, 72 : 493 - 507
  • [9] Preclinical evaluation of anti-CD37 antibody-targeted amanitin conjugates (ATAC) in B-cell malignancies.
    Voss, Stephanie
    Palfi, Aniko
    Mueller, Christoph
    Pahl, Andreas
    Hechler, Torsten
    Kulke, Michael
    CANCER RESEARCH, 2021, 81 (13)
  • [10] Development of a new fully human anti-CD20 monoclonal antibody for the treatment of B-cell malignancies
    Bornstein, Gadi Gazit
    Queva, Christophe
    Tabrizi, Mohammad
    van Abbema, Anne
    Chavez, Carlos
    Wang, Ping
    Foord, Orit
    Ahluwalia, Kiran
    Laing, Naomi
    Raja, Sandhya
    Wen, Shenghua
    Green, Larry L.
    Yang, Xiaodong
    Webster, Carl
    Stewart, Ross
    Blakey, David
    INVESTIGATIONAL NEW DRUGS, 2010, 28 (05) : 561 - 574
12345