Near infrared fluorescence for image-guided surgery

被引：109

作者：

Gibbs, Summer L. ^{[1
]}

机构：

[1] Oregon Hlth & Sci Univ, Ctr Spatial Syst Biomed, Knight Canc Inst, Dept Biomed Engn, Portland, OR 97201 USA

来源：

QUANTITATIVE IMAGING IN MEDICINE AND SURGERY | 2012年 / 2卷 / 03期

关键词：

Near infrared (NIR); image-guided surgery;

D O I：

10.3978/j.issn.2223-4292.2012.09.04

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Near infrared (NIR) image-guided surgery holds great promise for improved surgical outcomes. A number of NIR image-guided surgical systems are currently in preclinical and clinical development with a few approved for limited clinical use. In order to wield the full power of NIR image-guided surgery, clinically available tissue and disease specific NIR fluorophores with high signal to background ratio are necessary. In the current review, the status of NIR image-guided surgery is discussed along with the desired chemical and biological properties of NIR fluorophores. Lastly, tissue and disease targeting strategies for NIR fluorophores are reviewed.

引用

页码：177 / 187

页数：11

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