Seizures, Epilepsy, and Circadian Rhythms

被引:3
|
作者
Hofstra-van Oostveen, Wytske A. [1 ]
de Weerd, Al W. [2 ,3 ]
机构
[1] Med Spectrum Twente Hosp, Dept Neurol, Postbus 50 000, NL-7500 KA Enschede, Netherlands
[2] Dept Clin Neurophysiol, NL-8025 BV Zwolle, Netherlands
[3] Sleep Ctr SEIN, NL-8025 BV Zwolle, Netherlands
关键词
Circadian rhythmicity; Seizures; Epilepsy; Melatonin;
D O I
10.1016/j.jsmc.2011.12.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Interaction between circadian rhythmicity and epilepsy or seizures may have important implications in diagnostic and therapeutic options, as EEGs and treatment can be individualized. In studies in humans and animals, seizure occurrence has been shown to have a 24-hour (ie, diurnal) rhythmicity, depending on the type of seizure and lobe of origin. A pilot study in humans suggested that temporal and frontal seizures not only occur in diurnal patterns but also are time locked to the circadian phase. A study in rats showed a true endogenous-mediated circadian rhythm in seizure occurrence in a rodent model of limbic epilepsy.
引用
收藏
页码:99 / +
页数:8
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