SCREENING FOR WILMS-TUMOR IN HIGH-RISK INDIVIDUALS

被引：24
|
作者：
CLERICUZIO, CL [1 ]
JOHNSON, C [1 ]
机构：
[1] UNIV CALGARY, CHILDRENS HOSP, DEPT MED GENET, CALGARY, AB, CANADA
来源：
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA | 1995年 / 9卷 / 06期
关键词：
D O I：
10.1016/S0889-8588(18)30043-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Clinicians have long recognized the syndromic association between Wilms tumor and a variety of genetic disorders. The recent identification of molecular mechanisms associated with the development of certain Wilms tumors may allow for precise identification and improved tumor screening for high-risk individuals. This article reviews the clinical and molecular features associated with Wilms tumor in addition to the introduction of strategies guidingits surveillance. The implementation of presymptomatic tumor surveillance in high-risk individuals should lead to early diagnosis and treatment of Wilms tumor.
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收藏
页码：1253 / +
页数：1
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