Hyperplastic Polyps, Serrated Adenomas, and the Serrated Polyp Neoplasia Pathway

被引:1
|
作者
Watson, Alan R. [1 ]
Jankowski, Janusz [1 ]
机构
[1] Canc Res UK, Histopathol Unit, 44 Lincolns Inn Fields, London WC2A 3PX, England
关键词
D O I
10.1007/s11888-007-0009-3
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
It was previously thought that adenomas gave rise to colorectal cancers and that other polyps were harmless. Serrated polyps-hyperplastic polyps, serrated adenomas, and sessile serrated adenomas-show distinct patterns of genetic and epigenetic mutation that suggest their role in an alternative pathway of colorectal cancer development. In parallel with these findings are improved demographic and histologic data that also indicate that a subset of serrated polyps are precursors of cancer.
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页码:3 / 9
页数:7
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