CEFTRIAXONE PLUS CONVENTIONAL OR SINGLE-DAILY DOSE AMIKACIN VERSUS CEFTAZIDIME AMIKACIN AS EMPIRIC THERAPY IN FEBRILE NEUTROPENIC PATIENTS

被引：20

作者：

LEONI, F

CIOLLI, S

PASCARELLA, A

FANCI, R

CAPORALE, R

FERRINI, PLR

机构：

[1] USL 10-D,CATTEDRA,FLORENCE,ITALY

[2] USL 10-D,DIV EMATOL,FLORENCE,ITALY

来源：

CHEMOTHERAPY | 1993年 / 39卷 / 02期

关键词：

GRANULOCYTOPENIC PATIENTS; CEFTRIXONE; CEFTAZIDIME; AMIKACIN;

D O I：

10.1159/000239118

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Results of antibiotic treatment in 144 febrile episodes during drug-induced granulocytopenia are reported. 63 episodes were treated with ceftazidime plus amikacin and 81 with ceftriaxone (CFX) using single daily doses combined with amikacin either divided in three doses (CFX-1 group) or administered as single doses (CFX-2 group). The response rates were 51, 80, and 57% respectively. In this study CFX was more effective than ceftazidime and amikacin provided better results when administered using the standard 8-hour scheduling.

引用

页码：147 / 152

页数：6

共 50 条

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