MOLECULAR-CLONING OF A CDNA-ENCODING A NOVEL SMALL GTP-BINDING PROTEIN

被引：8
|
作者：
KODA, T
KAKINUMA, M
机构：
[1] Section of Bacterial Infection, Institute of Immunological Science, Hokkaido University, Kita-ku, Sapporo, 060, Kita-15
来源：
FEBS LETTERS | 1993年 / 328卷 / 1-2期
关键词：
GTP-BINDING PROTEIN; LYMPHOCYTE; MACROPHAGE; VESICULAR TRANSPORT;
D O I：
10.1016/0014-5793(93)80957-V
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A cDNA encoding a small GTP-binding protein, S10, was cloned from Jurkat cells. The deduced amino acid sequence of S10 had the structural features characteristic to this family of proteins with highest homology to rab subfamily. Northern blot analysis revealed that this gene is expressed only in lymphoid cell lines and a histiocytic leukemia, U937. Hence, it should have a specialized function in cells derived from the hematopoietic stem cell.
引用
收藏
页码：21 / 24
页数：4
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