INCREASED C-FOS EXPRESSION IN NUCLEUS OF THE SOLITARY TRACT CORRELATED WITH CONDITIONED TASTE-AVERSION TO SUCROSE IN RATS

被引:95
|
作者
HOUPT, TA [1 ]
PHILOPENA, JM [1 ]
WESSEL, TC [1 ]
JOH, TH [1 ]
SMITH, GP [1 ]
机构
[1] CORNELL UNIV,COLL MED,BURKE MED RES INST,DEPT NEUROSCI,WHITE PLAINS,NY 10605
关键词
GUSTATORY NERVE; IMMEDIATE-EARLY GENE; GENE EXPRESSION; IMMUNOREACTIVITY; LEARNING; MEMORY;
D O I
10.1016/0304-3940(94)90648-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The pattern of neuronal activation in the rat nucleus of the solitary tract (NTS) in response to a standard gustatory stimulus was examined using c-Fos-like immunoreactivity (c-FLI) before and after conditioned taste aversion (CTA) formation. While unconditioned oral infusions of sucrose solution did not induce c-FLI in the NTS, after three pairings of sucrose with lithium chloride injections, sucrose induced c-FLI in the medial intermediate NTS 1 h after oral infusion. Extinction of the CTA by repeated infusions of sucrose alone reversed the induction of c-FLI.
引用
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页码:1 / 5
页数:5
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