METRONIDAZOLE AND DRUG-RESISTANCE

被引：106
|
作者：
JOHNSON, PJ
机构：
[1] Patricia J. Johnson is at the Department of Microbiology and Immunology, University of California, Los Angeles
来源：
PARASITOLOGY TODAY | 1993年 / 9卷 / 05期
关键词：
D O I：
10.1016/0169-4758(93)90143-4
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
In recent years, the basis of metronidazole resistance has been examined in anaerobic protozoa, such as Trichomonas and Giardia, as well as anaerobic bacteria, such as Bacteroides and Clostridium. In this review, Patricia Johnson looks at a variety of mechanisms that lead to reduced susceptibility of these pathogens to the drug The frequent correlation between metronidazole resistance and inefficient drug activation suggests that this is the level at which drug resistance operates.
引用
收藏
页码：183 / 186
页数：4
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