Detection of copper ions and glutathione based on off-on fluorescent graphene quantum dots

被引：1
|
作者：
Song Fengjuan [1 ]
Ai Yongling [1 ]
Zhong Wenying [1 ,2 ]
Wang Jing [1 ,2 ]
机构：
[1] China Pharmaceut Univ, Minist Educ, Key Lab Biomed Funct Mat, Nanjing 210009, Jiangsu, Peoples R China
[2] China Pharmaceut Univ, Minist Educ, Key Lab Drug Qual Control & Pharmacovigilance, Nanjing 210009, Jiangsu, Peoples R China
来源：
JOURNAL OF CHINA PHARMACEUTICAL UNIVERSITY | 2018年 / 49卷 / 01期
基金：
中国国家自然科学基金;
关键词：
graphene quantum dots; Cu2+; glutathione; fluorescence quenching-recovery; content determination;
D O I：
10.11665/j.issn.1000-5048.20180112
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
We developed a rapid method to detect Cu2+ and glutathione (GSH) based on the fluorescence quenching-recovery properties of graphene quantum dots (GQDs), which were synthesized by the gentle oxidation of graphite powder. The results revealed that the fluorescence intensity of GQDs versus concentration of Cu2+ and GSH had good linearity, with the detection limits of 0.01 and 0.1 mmol/L, respectively. The fluorescence quenching was linearly proportional to the concentrations of Cu2+ ranging from 1.0 to 10.0 mmol/L; the fluorescence intensity was linearly enhanced with the concentrations of GSH ranging from 0.1 to 1.0 mmol/L. In addition, the method was successfully applied to the determination of real samples with recoveries falling between 93%-101% and 96%-107%, respectively. This method is simple, accurate and precise. There was no interference with other familiar co-existing metal ions and potential materials.
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收藏
页码：87 / 92
页数：6
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