To talk about women and their protection from human rights, is to analize international instruments, constitutional reforms and the General Law of Victims, to understand the new paradigms of defense to be able to support them. From cases like that of Martin Castaneda Gutman; Gonzalez and others (cotton field) and Rosendo Radilla Pacheco, in which the Inter-American Court of Human Rights (IACHR) determined the international responsibility of the Mexican State. The Radilla Pacheco case is iconic for Mexico, because for the first time the IACHR directly linked the Judiciary of the Federation to comply with concrete reparation measures. This situation generates important changes to the Political Constitution of the United Mexican States, to include a series of reforms aimed at better protection of human rights, highlighting in terms of the subject matter discussed here the Article 1 and 20, Section C. Likewise, the General Law on Victims prioritizes its attention with the inclusion of a series of actions to be carried out by the Commissions for Victim Assistance in each of the states; this is intended to give real attention to all those victims of crime or violations of their human rights.