MYCOBACTEREMIA AND GRANULOMATOUS HEPATITIS FOLLOWING INITIAL INTRAVESICAL BACILLUS-CALMETTE-GUERIN INSTILLATION FOR BLADDER-CARCINOMA

被引：0
|
作者：
PROCTOR, DD
CHOPRA, S
RUBENSTEIN, SC
JOKELA, JA
UHL, L
机构：
[1] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT MED,DIV GASTROENTEROL,DANA 501,330 BROOKLINE AVE,BOSTON,MA 02215
[2] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT MED,DIV INFECT DIS,BOSTON,MA 02215
[3] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT SURG,DIV UROL,BOSTON,MA 02215
[4] HARVARD UNIV,BETH ISRAEL HOSP,SCH MED,DEPT PATHOL,BOSTON,MA 02215
来源：
AMERICAN JOURNAL OF GASTROENTEROLOGY | 1993年 / 88卷 / 07期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
We describe the first case of mycobacteremia and granulomatous hepatitis occurring after the initial intravesical instillation of bacillus Calmette-Guerin (BCG) for bladder cancer. Eight days after BCG instillation, a liver biopsy revealed well-defined granulomas and acid-fast bacilli. A blood culture drawn 8 h after BCG instillation grew Mycobacterium bovis. We summarize the reported complications of BCG intravesical immunotherapy, the associated risk factors, and discuss options for treatment. Although rare, mycobacteremia and granulomatous hepatitis are important systemic side effects of intravesical instillation of BCG for bladder cancer, and should be considered in any patient who presents with persistent fever and abnormal liver function tests after instillation of BCG.
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页码：1112 / 1115
页数：4
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