A fast, simple and convenient procedure for the synthesis of fused pyrimidinone derivatives by using [Hmim][HSO4] as a green, efficient and reusable catalyst under solvent-free conditions

被引:0
|
作者
Khazdooz, Leila [1 ]
Zarei, Amin [2 ]
Hajipour, Abdol Reza [3 ,4 ]
Sheikhan, Nafisehsadat [5 ]
机构
[1] Islamic Azad Univ, Dept Sci, Khorasgan Branch, Esfahan 81595158, Iran
[2] Islamic Azad Univ, Dept Sci, Fasa Branch, Fars 7461713591, Iran
[3] Univ Wisconsin, Sch Med, Dept Pharmacol, Madison, WI 53706 USA
[4] Isfahan Univ Technol, Pharmaceut Res Lab, Esfahan 84156, Iran
[5] Islam Azad Univ, Dept Sci, Najafabad Branch, Esfahan, Iran
来源
IRANIAN JOURNAL OF CATALYSIS | 2012年 / 2卷 / 04期
关键词
Pyrimidinone; Methylimidazolium hydrogen sulfate; Bronsted acidic ionic liquid; Biginelli-type reaction;
D O I
暂无
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In the present of methylimidazolium hydrogen sulfate, the synthesis of arylidene heterobicyclic pyrimidinones is studied by condensation of aromatic aldehyde, cyclopentanone, and urea or thiourea. Using solvent-free conditions, non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.
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页码:173 / 178
页数:6
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