RED-BLOOD-CELL MEMBRANE LIPID-COMPOSITION IN IRON-DEFICIENCY ANEMIA PATIENTS DURING TREATMENT

Red blood cell membrane lipid composition was studied in 51 iron deficiency anemia patients, in 10 of them during ferrotherapy. It was noted that red blood cell membranes contained increased total levels of lipids, phospholipids and significantly decreased levels of cholesterol esters and lysophospholipids. During the treatment, in the presence of a distinct process of the recovery of disturbed lipid composition of red blood cell membranes, a significant increase was recorded in the content of triglycerides, phosphatidyl amines, while phosphatidyl and cardiolipin levels were significantly lowered. Red blood cell membrane lipid content in iron deficiency anemia patients and its dynamics in the process of their treatment might serve, as an additional criteria of the body saturation with iron.