ALKALOIDS FROM AMARYLLIDACEAE .2. ALKALOIDS OF CRININE CLASS FROM PANCRATIUM-MARITIMUM

Seven Amaryllidaceae alkaloids of the crinine class have been isolated hom the bulbs of Pancratium maritimum of Turkish origin. Five of these, namely (+)-haemanthamine (1), (+)-buphanisine (2), (-)-crinine (3), (-)-3-beta methoxy 6 alpha, beta-dihydroxy-1,2-dehydrocrinane (4a,4b), (-)-6,11 alpha, beta-dihydroxy-3-methoxy-1,2-dehymucrinane (5a,b) have been described previously, while the other two (-)-3 beta, 11 alpha-dihydroxy-1,2-dehydrocrinaoe (6) and (-)8-hydroxy-9-methoxyainine (7) represent new compounds. The structure and stereochemistry of these alkaloids have been determined by the detailed investigation of spectroscopic techniques.