REFERENCE VALUES OF PLASMA AND URINE CREATININE AND CREATININE CLEARANCE IN NORMAL-CHILDREN

We report reference values of plasma and urine creatinine and creatinine clearance for children between 3 and 14 years of age, based on observations in 521 children for plasma creatinine and 361 for creatinine clearance. Plasma creatinine increased through childhood; there was no difference between the sexes. Urine creatinine should be expressed in mg/kg/24 h since this abolishes the difference between the sexes and diminishes the increase with age. Creatinine clearance increases with age and there was no difference between the sexes. The reference values for creatinine clearance in children are presented in two age groups which differ significantly.