FALSELY ELEVATED SERUM DIGOXIN LEVELS SECONDARY TO ENDOGENOUS DIGOXIN-LIKE IMMUNOREACTIVE SUBSTANCES

被引：6
|
作者：
KOOBATIAN, TJ
ROBERTS, JR
机构：
[1] MISERICORDIA HOSP,MERCY CATHOLIC MED CTR,DEPT EMERGENCY MED,DIV TOXICOL,PHILADELPHIA,PA 19143
[2] MED COLL PENN,DEPT EMERGENCY MED,DIV TOXICOL,PHILADELPHIA,PA
来源：
ACADEMIC EMERGENCY MEDICINE | 1995年 / 2卷 / 04期
关键词：
DIGOXIN; ASSAY; IMMUNOREACTIVE SUBSTANCES; POISONING; OVERDOSE; TOXICOLOGY;
D O I：
10.1111/j.1553-2712.1995.tb03231.x
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Endogenous digoxin-like immunoreactive substances (DLIS) are produced by the human body and can be significantly elevated in specific clinical conditions. Commercially available digoxin assays do not have the specificity to fully distinguish DLIS from exogenous digoxin, though DLIS do not possess the same therapeutic properties as do the drug. The resultant artificial elevation of a reported digoxin level or a completely factitious level in a patient not taking the drug can have clinically significant consequences.
引用
收藏
页码：322 / 326
页数：5
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