SYNTHESIS OF SOME MIMICS OF NUCLEOSIDE TRIPHOSPHATES

被引：39

作者：

COE, DM

HILPERT, H

NOBLE, SA

PEEL, MR

ROBERTS, SM

STORER, R

机构：

[1] GLAXO GRP RES LTD,DEPT MED CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND

[2] GLAXO INC,DEPT CHEM,RES TRIANGLE PK,NC

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 05期

关键词：

D O I：

10.1039/c39910000312

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The nucleotide analogues 10, 13, 14 and 20 have been synthesised; the latter phosphonate was converted into the diphosphoryl-phosphonate 21 and this compound was shown to be a potent inhibitor of HIV-coded reverse transcriptase.

引用

页码：312 / 314

页数：3

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