Basosquamous Cell Carcinoma Developing from a Renal Transplantation Recipient

被引：0
|
作者：
Tsukada, Akira [1 ]
Fujimura, Taku [1 ]
Furudate, Sadanori [1 ]
Kambayashi, Yumi [1 ]
Hashimoto, Akira [1 ]
Aiba, Setsuya [1 ]
机构：
[1] Tohoku Univ, Grad Sch Med, Dept Dermatol, Sendai, Miyagi, Japan
来源：
CASE REPORTS IN DERMATOLOGY | 2012年 / 4卷 / 03期
关键词：
Basosquamous cell carcinoma; Immunosuppressive cells; CD163(+) M2 macrophage; Carcinogenesis;
D O I：
10.1159/000345095
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
We describe a case of basosquamous cell carcinoma arising from a 52-year-old Japanese renal transplantation recipient (RTR). In the present case, we investigated the immunohistochemical profiles of tumor-infiltrating lymphocytes, focusing on cytotoxic granules, granulysin-bearing cells and immunosuppressive cells, such as regulatory T cells and tumor-associated macrophages. Our present study suggests some of the possible mechanisms for the carcinogenesis of cutaneous malignancy in RTRs.
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收藏
页码：227 / 232
页数：6
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