INCIDENTAL LEWY-BODY DISEASE IN A PATIENT WITH REM-SLEEP BEHAVIOR DISORDER

被引：220
|
作者：
UCHIYAMA, M
ISSE, K
TANAKA, K
YOKOTA, N
HAMAMOTO, M
AIDA, S
ITO, Y
YOSHIMURA, M
OKAWA, M
机构：
[1] TOKYO METROPOLITAN TAMA GERIATR HOSP,DEPT PSYCHIAT,HIGASHIMURAYAMA,JAPAN
[2] TOKYO METROPOLITAN TAMA GERIATR HOSP,DEPT NEUROL,HIGASHIMURAYAMA,JAPAN
[3] TOKYO METROPOLITAN TAMA GERIATR HOSP,DEPT CLIN PATHOL,HIGASHIMURAYAMA,JAPAN
[4] TOKYO METROPOLITAN MED EXAMINERS OFF,DEPT CLIN PATHOL,TOKYO,JAPAN
来源：
NEUROLOGY | 1995年 / 45卷 / 04期
关键词：
D O I：
10.1212/WNL.45.4.709
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We studied an 84-year-old man with a 20-year history of nocturnal violent behavior during sleep, but no other clinically evident neuropsychiatric disorders. Polysomnographic investigations confirmed that he suffered from REM sleep behavior disorder (RED). Histopathologic examination revealed that he had Lewy body disease with a marked decrease of pigmented neurons in the locus ceruleus and substantia nigra. These histologic findings represent the first documented evidence of a loss of brainstem monoaminergic neurons in clinically idiopathic RED and suggest that Lewy body disease might provide an explanation for idiopathic RED in the aged.
引用
收藏
页码：709 / 712
页数：4
相关论文
共 50 条
  • [1] Lewy body disease in a patient with REM sleep disorder
    Negro, PJ
    Faber, R
    NEUROLOGY, 1996, 46 (05) : 1493 - 1493
  • [2] Polysomnographic Insights in REM-Sleep behavior disorder diagnosis in lewy body diseases
    van Heese, Eva
    Laansma, Max
    van Dijk, Karin
    Lemstra, Evelien
    Ringnalda, Miranda
    de Groot, Julia
    Koekenbier, Ronald
    Lemmerzaal, Janneke
    van Alphen, Juliette
    van den Heuvel, Odile
    van der Werf, Ysbrand
    JOURNAL OF SLEEP RESEARCH, 2024, 33
  • [3] REM-SLEEP BEHAVIOR DISORDER
    SCHENCK, CH
    HURWITZ, TD
    MAHOWALD, MW
    AMERICAN JOURNAL OF PSYCHIATRY, 1988, 145 (05): : 652 - 652
  • [4] REM-SLEEP BEHAVIOR DISORDER
    NOFZINGER, EA
    REYNOLDS, CF
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (11): : 820 - 820
  • [5] REM-SLEEP BEHAVIOR DISORDER
    SALZARULO, P
    JOURNAL OF SLEEP RESEARCH, 1994, 3 (03) : 192 - 192
  • [6] REM-SLEEP BEHAVIOR DISORDER
    BAHRO, M
    KATZMANN, KJ
    GUCKEL, F
    SUNGURTEKIN, I
    RIEMANN, D
    NERVENARZT, 1994, 65 (08): : 568 - 571
  • [7] Probable diffuse Lewy body disease presenting as REM sleep behavior disorder
    Turner, RS
    Chervin, RD
    Frey, KA
    Minoshima, S
    Kuhl, DE
    NEUROLOGY, 1997, 49 (02) : 523 - 527
  • [8] REM-SLEEP BEHAVIOR DISORDER AND PARKINSONS-DISEASE
    SILBER, MH
    AHLSKOG, JE
    NEUROLOGY, 1993, 43 (04) : A338 - A338
  • [9] REM-sleep behavior disorder in the elderly
    Chiu, H
    Lam, L
    EUROPEAN PSYCHIATRY, 2000, 15 : 322S - 322S
  • [10] REM-SLEEP BEHAVIOR DISORDER (RBD)
    NAVARRO, JF
    TORTAJADA, RE
    BEHAVIORAL PSYCHOLOGY-PSICOLOGIA CONDUCTUAL, 1994, 2 (03): : 323 - 330
12345