THE POTENTIAL ROLES OF LEUKOTRIENES IN BRONCHIAL-ASTHMA

被引：0
|
作者：
PIACENTINI, GL [1 ]
KALINER, MA [1 ]
机构：
[1] NIAID, CLIN INVEST LAB, ALLERG DIS SECT, BETHESDA, MD 20892 USA
来源：
AMERICAN REVIEW OF RESPIRATORY DISEASE | 1991年 / 143卷 / 05期
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D O I：
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中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Leukotrienes (LTs), in particular LTC4, LTD4, and LTE4, have been shown to be capable of participating in the induction of three related processes observed during the immediate reaction in bronchial asthma: edema formation, mucus secretion, and muscle contraction. Despite impressive evidence potentially implicating the LTs, the role of LTs in asthma is still unproved, and a positive answer to their critical actions in causing airflow obstruction will require studies with specific antagonists.
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页码：S96 / S99
页数：4
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