Evolution of Atypical Femur Fractures and the Association with Bisphosphonates

被引：0
|
作者：
Takemoto, Richelle C. [1 ]
McLaurin, Toni M. [1 ]
Tejwani, Nirmal [1 ]
Egol, Kenneth A. [1 ]
机构：
[1] NYU, Langone Med Ctr, Hosp Joint Dis, Dept Orthopaed Surg, 301 East 17th St, New York, NY 10003 USA
来源：
BULLETIN OF THE HOSPITAL FOR JOINT DISEASES | 2014年 / 72卷 / 01期
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D O I：
暂无
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
For almost 15 years bisphosphonates have been the mainstay of prevention and treatment of fragility fractures, particularly in post-menopausal women. As a result, there has been a decrease in fragility fractures, along with the health care costs associated with treating them. However, with all drugs, there are always concerns with side effects and potential complications. Atypical femur fractures have been observed in women taking bisphosphonates, a complication the drug was designed to prevent. There is no definitive link between bisphosphonates and atypical femur fractures and no protocol to managing these fractures. This review discusses the evolution and development of bisphosphonates and offers the latest information regarding evidence surrounding the link to atypical femur fractures.
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页码：104 / 109
页数：6
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