Medical Treatment of Missed Miscarriage before 24 Week of Gestation at Liaquat University Hospital

OBJECTIVE: The objective of this study was to determine the safety and efficacy of misoprostol in termination of missed miscarriage under 24-weeks gestation. METHODOLOGY: This descriptive observational study was conducted on 100 cases of missed miscarriage in the Department of Gynecology, Liaquat University Hospital, Hyderabad for the period of one year i.e. from 1stJanuary 2007 to 31stDecember 2007. Women with missed miscarriage of less than 24-weeks of gestation requiring termination of pregnancy were included in this study whereas Women with other types of miscarriage like incomplete, threatened miscarriages, gestational trophoblastic disease, liver disease and disturbed coagulation profiles were excluded from the study RESULTS: Mean age of the patients was 26.79 +/- 4.82 years. Fifty three (53%) women had no previous history of miscarriage. Average gestational age was 14.75 +/- 4.96 weeks. Forty four (44%) patients needed surgical treatment while 56% had complete miscarriage with medical (misoprostol) treatment. CONCLUSION: Misoprostol has proven to be a safe and effective method for the management of missed miscarriage.