THE SYNTHESIS OF PLICATIN-B VIA THE HECK REACTION

被引:17
|
作者
BATES, RW
GABEL, CJ
机构
[1] Department of Chemistry, University of North Texas, Denton, TX 76203
关键词
D O I
10.1016/S0040-4039(00)73632-X
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The anti-microbial natural product Plicatin B has been synthesized in 53% overall yield using a Heck reaction as the key step. The optimum conditions for this reaction have been determined. Halophenols proved much less reactive than their corresponding acetates.
引用
收藏
页码:3547 / 3550
页数:4
相关论文
共 50 条
  • [1] THE SYNTHESIS OF PLICATIN-B
    BATES, RW
    GABEL, CJ
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 205 : 304 - ORGN
  • [2] PLICATIN-A AND PLICATIN-B 2 PHENOLIC CINNAMATES FROM PSORALEA-PLICATA
    RASOOL, N
    KHAN, AQ
    MALIK, A
    PHYTOCHEMISTRY, 1990, 29 (12) : 3979 - 3981
  • [3] PLICATIN-B, THE ANTIMICROBIAL PRINCIPLE OF PSORALEA-JUNCEA
    SCHMITT, A
    TELIKEPALLI, H
    MITSCHER, LA
    PHYTOCHEMISTRY, 1991, 30 (11) : 3569 - 3570
  • [4] Synthesis of hydroxystilbenes and their derivatives via Heck reaction
    Farina, Angela
    Ferranti, Carolina
    Marra, Carolina
    Guiso, Marcella
    Norcia, Giulia
    NATURAL PRODUCT RESEARCH, 2007, 21 (06) : 564 - 573
  • [5] A new synthesis of flavonoids via Heck reaction
    Bianco, A
    Cavarischia, C
    Farina, A
    Guiso, M
    Marra, C
    TETRAHEDRON LETTERS, 2003, 44 (51) : 9107 - 9109
  • [6] Total synthesis of anthocyanidins via Heck reaction
    Bianco, A
    Cavarischia, C
    Guiso, M
    NATURAL PRODUCT RESEARCH, 2006, 20 (01) : 93 - 97
  • [7] Efficient synthesis of pyridylacrylonitriles via the Heck reaction
    Mei, Kui
    Wang, Junbo
    Hu, Xianming
    SYNTHETIC COMMUNICATIONS, 2006, 36 (17) : 2525 - 2532
  • [8] Synthesis of 2-arylmaleimides via the Heck reaction
    Roshchin, Alexander I.
    Polunin, Evgeny V.
    MENDELEEV COMMUNICATIONS, 2008, 18 (06) : 332 - 333
  • [9] Synthesis of latonduine derivatives via intramolecular Heck reaction
    Putey, Aurelien
    Joucla, Lionel
    Picot, Laurent
    Besson, Thierry
    Joseph, Benoit
    TETRAHEDRON, 2007, 63 (04) : 867 - 879
  • [10] Synthesis of enantiopure estrone via a double Heck reaction
    Tietze, LF
    Nöbel, T
    Spescha, M
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (35) : 8971 - 8977