THE STEM-LOOP STRUCTURE OF THE CIS-ENCAPSIDATION SIGNAL IS HIGHLY CONSERVED IN NATURALLY-OCCURRING HEPATITIS-B VIRUS VARIANTS

被引：43
|
作者：
LASKUS, T
RAKELA, J
PERSING, DH
机构：
[1] MAYO CLIN & MAYO FDN,DEPT EXPLT PATHOL & LAB MED,ROCHESTER,MN 55905
[2] MAYO CLIN & MAYO FDN,DEPT GASTROENTEROL,ROCHESTER,MN 55905
来源：
VIROLOGY | 1994年 / 200卷 / 02期
关键词：
D O I：
10.1006/viro.1994.1247
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The region encoding the stem-loop structure of the HBV cis-encapsidation signal was sequenced in 87 patients with Various terms of hepatitis. Altogether, 20 nucleotide substitutions were found; 15/20 were predicted to increase the stability of the stem-loop structure. Substitutions likely to decrease the stability of the cis-encapsidation signal were not observed. (C) 1994 Academic Press, Inc.
引用
收藏
页码：809 / 812
页数：4
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