Impact of polymorphisms of the GGCX gene on maintenance warfarin dose in Chinese populations: Systematic review and meta-analysis

被引：14

作者：

Tian, Lihong ^{[2
]}

Zhang, Jinhua ^{[1
]}

Xiao, Shiji ^{[2
]}

Huang, Jinlong ^{[2
]}

Zhang, Yuanyuan ^{[2
]}

Shen, Jianzhen ^{[2
]}

机构：

[1] Fujian Med Univ, Union Hosp, Dept Pharm, Fuzhou 350001, Fujian, Peoples R China

[2] Fujian Med Univ, Union Hosp, Fujian Insitute Hematol, Fujian Prov Key Lab Hematol, Xinquan Rd 29, Fuzhou 350001, Fujian, Peoples R China

来源：

META GENE | 2015年 / 5卷

基金：

中国国家自然科学基金;

关键词：

Warfarin; GGCX; Gene polymorphisms; Systematic review; Meta-analysis; Chinese;

D O I：

10.1016/j.mgene.2015.05.003

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The meta-analysis was conducted to investigate the impact of gamma-glutamyl carboxylase (GGCX) on maintenance warfarin dose. 8 studies were included, focusing on the impact of GGCX single nucleotide polymorphisms (SNPs) on mean daily warfarin dose (MDWD). GGCX (rs699664; AA versus GG, GA versus GG, A versus GG) and GGCX (rs12714145; GA versus GG, AA versus GG, A versus GG) showed no significant differences on mean daily warfarin dose (MDWD). This meta-analysis was the first to report the relationship between GGCX SNPs and MDWD in Chinese populations. No evidence could be found in the relationship between SNPs of GGCX (rs699664 and rs12714145) and maintenance warfarin dose. (C) 2015 The Authors. Published by Elsevier B.V.

引用

页码：43 / 54

页数：12

共 50 条

[1] Impact of polymorphisms of the GGCX gene on maintenance warfarin dose: systematic review and meta-analysis
Zhang, Jinhua
Tian, Lihong
[J]. PHARMACOTHERAPY, 2015, 35 (11): : E206 - E206
[2] Impact of the CYP4F2 gene polymorphisms on the warfarin maintenance dose: A systematic review and meta-analysis
Sun, Xue
Yu, Wan-Ying
Ma, Wan-Le
Huang, Li-Hua
Yang, Guo-Ping
[J]. BIOMEDICAL REPORTS, 2016, 4 (04) : 498 - 506
[3] Impact of gamma-glutamyl carboxylase gene polymorphisms on warfarin dose requirement: A systematic review and meta-analysis
Sun, Yifan
Wu, Zhitong
Li, Shan
Qin, Xue
Li, Taijie
Xie, Li
Deng, Yan
Chen, Junqing
[J]. THROMBOSIS RESEARCH, 2015, 135 (04) : 739 - 747
[4] Impact of CYP2C19 gene polymorphisms on warfarin dose requirement: a systematic review and meta-analysis
Wang, Dongxu
Yong, Ling
Zhang, Qing
Chen, Hao
[J]. PHARMACOGENOMICS, 2022, 23 (16) : 903 - 911
[5] Impact of VKORC1 gene polymorphisms on warfarin maintenance dosage: A novel systematic review and meta-analysis of 53 studies
Tang, Wei
Shi, Qing-ping
Ding, Feng
Yu, Mei-Ling
Hua, Jian
Wang, Yong-xin
[J]. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2017, 55 (04) : 304 - 321
[6] Impact of GGCX polymorphisms on warfarin dose requirements in atrial fibrillation patients
Jiang, Nian-Xin
Xu, Ying-Hui
Xia, Jing-Wen
Jiang, Bing
Li, Yan-Song
[J]. TURKISH JOURNAL OF MEDICAL SCIENCES, 2017, 47 (04) : 1239 - 1246
[7] Influence of NQO1 Polymorphisms on Warfarin Maintenance Dose: A Systematic Review and Meta-Analysis (rs1800566 and rs10517)
Tian, Lihong
Xiao, Pingping
Zhou, Bingrong
Chen, Yishan
Kang, Lijuan
Wang, Qingqing
Lin, Jianfeng
Son, Min
Wu, Qingxiu
[J]. CARDIOVASCULAR THERAPEUTICS, 2021, 2021
[8] Genetic Factors Influencing Warfarin Dose in Han Chinese Population: A Systematic Review and Meta-Analysis of Cohort Studies
Zinan Zhao
Fei Zhao
Xiang Wang
Deping Liu
Junpeng Liu
Yatong Zhang
Xin Hu
Ming Zhao
Chao Tian
Shujie Dong
Pengfei Jin
[J]. Clinical Pharmacokinetics, 2023, 62 : 819 - 833
[9] Genetic Factors Influencing Warfarin Dose in Han Chinese Population: A Systematic Review and Meta-Analysis of Cohort Studies
Zhao, Zinan
Zhao, Fei
Wang, Xiang
Liu, Deping
Liu, Junpeng
Zhang, Yatong
Hu, Xin
Zhao, Ming
Tian, Chao
Dong, Shujie
Jin, Pengfei
[J]. CLINICAL PHARMACOKINETICS, 2023, 62 (06) : 819 - 833
[10] The Impact of PCSK9 Gene Polymorphisms on Ischemic Stroke: A Systematic Review and Meta-Analysis
Wang, Jianhong
Li, Shuang
Ren, Yi
Wang, Guiquan
Li, Weirong
[J]. JOURNAL OF INTEGRATIVE NEUROSCIENCE, 2024, 23 (03)

← 1 2 3 4 5 →