CLINICAL-EVIDENCE OF SYSTEMIC PERSISTENCE OF BACILLUS CALMETTE-GUERIN - LONG-TERM PULMONARY BACILLUS CALMETTE-GUERIN INFECTION AFTER INTRAVESICAL THERAPY FOR BLADDER-CANCER AND SUBSEQUENT CYSTECTOMY

被引：14
|
作者：
BOHLE, A
KIRSTEN, D
SCHRODER, KH
KNIPPER, A
FORNARA, P
MAGNUSSEN, H
JOCHAM, D
机构：
[1] GROSSHANSDORF HOSP,DEPT PNEUMOL & THORAC SURG,LUBECK,GERMANY
[2] NATL REFERENCE CTR MYOBACTERIA,BORSTEL RES INST,LUBECK,GERMANY
来源：
JOURNAL OF UROLOGY | 1992年 / 148卷 / 06期
关键词：
BCG VACCINE; IMMUNOTHERAPY; MYCOBACTERIA; BLADDER NEOPLASMS; COMPLICATIONS;
D O I：
10.1016/S0022-5347(17)37063-5
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A patient with urothelial bladder carcinoma is reported who suffered from culture proved pulmonary bacillus Calmette-Guerin (BCG) infection 14 months after a single course of intravesical BCG and 11 months after subsequent radical cystectomy for progressive cancer. This unusual case raises the question of the ultimate fate of intravesically instilled BCG and the possible persistence of these mycobacteria in remote organs. Systemic spread and dormant survival at least in some cases are suggested, and therapeutic and diagnostic consequences are discussed.
引用
收藏
页码：1894 / 1897
页数：4
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