CARCINOGEN-DNA ADDUCTS IN HUMAN ALVEOLAR MACROPHAGES

被引：0
|
作者：
IZZOTTI, A [1 ]
BAGNASCO, M [1 ]
ROSSI, GA [1 ]
DEFLORA, S [1 ]
机构：
[1] SAN MARTINO HOSP,DIV PNEUMOL 1,GENOA,ITALY
来源：
RESPIRATION | 1992年 / 59卷
关键词：
CARCINOGEN-DNA ADDUCTS; PULMONARY ALVEOLAR MACROPHAGES; BRONCHOALVEOLAR LAVAGE; CIGARETTE SMOKE; HUMAN MONITORING; SYNCHRONOUS FLUORESCENCE; SPECTROPHOTOMETRY;
D O I：
暂无
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The occurrence of 7-beta,8-alpha-dihydroxy-(9-alpha,10-alpha)-epoxy-7,8,9,10- tetrahydrobenzo(a)pyrene (BPDE-)-DNA adducts was investigated by synchronous fluorescence spectrophotometry in human pulmonary alveolar macrophages (PAM) collected by bronchoalveolar lavage. In preliminary assays BPDE-DNA adducts were consistently detected in PAM of smokers, whereas samples from nonsmokers did not exhibit specific peaks.
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页码：33 / 34
页数：2
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