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ELEVATED SERUM PROGESTERONE LEVELS ON THE DAY OF HUMAN CHORIONIC-GONADOTROPIN ADMINISTRATION IN IN-VITRO FERTILIZATION CYCLES DO NOT ADVERSELY AFFECT EMBRYO QUALITY
被引:0
|作者:
SILVERBERG, KM
MARTIN, M
OLIVE, DL
BURNS, WN
SCHENKEN, RS
机构:
关键词:
IN VITRO FERTILIZATION;
FROZEN EMBRYO TRANSFER;
PROGESTERONE;
EMBRYO QUALITY;
D O I:
暂无
中图分类号:
R71 [妇产科学];
学科分类号:
100211 ;
摘要:
Objective: To assess the effect of an elevated serum P level on the day of hCG administration in an IVF cycle on resulting embryos by evaluating their performance at subsequent frozen ET. Design: A retrospective study. Participants: Ninety-six consecutive patients undergoing frozen ET cycles were studied in a tertiary care center. Main Outcome Measures: Serum obtained on the day of hCG administration in an IVF cycle was assayed for E(2) and P by RIA. The main outcome measured was the development of a clinical pregnancy in a subsequent frozen ET cycle. Results: Using a previously described breakpoint in serum P concentration of 0.9 ng/mL (2.86 nmol/L), 8 of 69 (11.6%) frozen ETs in which embryos from low P level IVF cycles were transferred and 7 of 27 (25.9%) frozen ETs of embryos from elevated P level IVF cycles were transferred resulted in the development of clinical pregnancies. Although this does not clearly demonstrate superiority of embryos obtained from elevated P cycles, employing a power calculation, the probability that the pregnancy rate in the elevated serum P group is at least equal to the observed rate in the low P group is 92.8%.
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页码:508 / 513
页数:6
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