ELEVATED SERUM PROGESTERONE LEVELS ON THE DAY OF HUMAN CHORIONIC-GONADOTROPIN ADMINISTRATION IN IN-VITRO FERTILIZATION CYCLES DO NOT ADVERSELY AFFECT EMBRYO QUALITY

被引:0
|
作者
SILVERBERG, KM
MARTIN, M
OLIVE, DL
BURNS, WN
SCHENKEN, RS
机构
关键词
IN VITRO FERTILIZATION; FROZEN EMBRYO TRANSFER; PROGESTERONE; EMBRYO QUALITY;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To assess the effect of an elevated serum P level on the day of hCG administration in an IVF cycle on resulting embryos by evaluating their performance at subsequent frozen ET. Design: A retrospective study. Participants: Ninety-six consecutive patients undergoing frozen ET cycles were studied in a tertiary care center. Main Outcome Measures: Serum obtained on the day of hCG administration in an IVF cycle was assayed for E(2) and P by RIA. The main outcome measured was the development of a clinical pregnancy in a subsequent frozen ET cycle. Results: Using a previously described breakpoint in serum P concentration of 0.9 ng/mL (2.86 nmol/L), 8 of 69 (11.6%) frozen ETs in which embryos from low P level IVF cycles were transferred and 7 of 27 (25.9%) frozen ETs of embryos from elevated P level IVF cycles were transferred resulted in the development of clinical pregnancies. Although this does not clearly demonstrate superiority of embryos obtained from elevated P cycles, employing a power calculation, the probability that the pregnancy rate in the elevated serum P group is at least equal to the observed rate in the low P group is 92.8%.
引用
收藏
页码:508 / 513
页数:6
相关论文
共 50 条