IN-VITRO ANTIOXIDANT AND CYTOTOXIC POTENTIAL OF CALOTROPIS PROCERA (R. BR.) ROOT

被引：1

作者：

Faruki, Md. Zakaria ^{[1
]}

Jha, Mithilesh Kumar ^{[2
]}

Rahman, Md. Mofizur ^{[1
]}

Alam, M. B. ^{[3
]}

Mazumder, M. E. H. ^{[4
]}

Rana, Md. Sohel ^{[4
]}

机构：

[1] Bangladesh Univ, Dept Pharm, Dhaka 1207, Bangladesh

[2] Pokhara Univ, Sch Hlth & Allied Sci, Dept Pharm, Lekhnath 12, Pokhara, Nepal

[3] Atish Dipankar Univ Sci & Technol, Dept Pharm, Dhaka, Bangladesh

[4] Jahangirnagar Univ, Dept Pharm, Dhaka, Bangladesh

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH | 2011年 / 2卷 / 08期

关键词：

Calotropis procera; Free radical scavenging; In vitro antioxidant; Cytotoxicity;

D O I：

10.13040/IJPSR.0975-8232.2(8).2132-35

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This study evaluated the in vitro antioxidant and cytotoxic potential of methanolic extract of the root of Calotropis procera (R. BR.). The Antioxidant activity of the extract was investigated by the In-vitro AntiOxidant activity (DDPH Scavenging activity) assays. The IC50 of the Calotropis procera studied by the above mention method was found below 100 mu g/ml which indicates the potent antioxidant activity of the plant. The extract of the root of Calotropis procera also demonstrated a strong cytotoxic activity against brine shrimp nauplii with an LC50 value of 2.931 mu g/ml.

引用

页码：2132 / 2135

页数：4

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