ENHANCED URINARY SPONTANEOUS LUMINESCENCE IN DUCHENNE MUSCULAR-DYSTROPHY

被引:6
|
作者
REYES, J
SALIMHANNA, M
LISSI, EA
VIDELA, LA
HOLMGREN, J
机构
[1] SOC PRO AYUDA NINO LISIADO, INST REHABIL INFANTIL, SANTIAGO, CHILE
[2] UNIV VALPARAISO, FAC MED, DEPT BIOL, VALPARAISO, CHILE
[3] UNIV SANTIAGO CHILE, FAC CIENCIA, DEPT QUIM, SANTIAGO, CHILE
[4] UNIV CHILE, FAC MED, DEPT BIOQUIM, SANTIAGO, CHILE
关键词
URINARY LUMINESCENCE; DUCHENNE MUSCULAR DYSTROPHY; OXIDATIVE STRESS; FREE RADICALS;
D O I
10.1016/0891-5849(94)90203-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Urinary spontaneous visible luminescence is enhanced in children with Duchenne Muscular Dystrophy (DMD). This result is indicative of systemic oxidative stress in DMD patients. It is proposed that measurement of the urinary luminescence could be employed to follow the progress of the disease, as well as the response of the patients to antioxidant therapy.
引用
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页码:851 / 853
页数:3
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