Electron microscopic analysis was used to study the ultrastructural changes taking place in rat soleus muscle following intraperitoneal administration of pure heroin. Degenerative changes observed consisted primarily of hypercontracted fibers at different stages of development. Evidence of regeneration was also found. Results show the myotoxic effect of pure heroin on skeletal muscle. The pathogenesis of muscle damage is discussed.
机构:
Queens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USAQueens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USA
Alshamam, Mohsen S.
Sumbly, Vikram
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Queens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USAQueens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USA
Sumbly, Vikram
Nso, Nso
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Queens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USAQueens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USA
Nso, Nso
Saliaj, Merjona
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Queens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USAQueens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USA
Saliaj, Merjona
Gurung, Dawa O.
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Queens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USAQueens Hosp Ctr, Icahn Sch Med Mt Sinai, Internal Med, New York, NY 11432 USA
机构:
Chinese Peoples Liberat Army Gen Hosp, Dept Neurol, Beijing 100853, Peoples R China
Jincheng Gen Hosp, Dept Neurol, Jincheng, Shanxi, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept Neurol, Beijing 100853, Peoples R China
Li, Li
Yu, Shengyuan
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Chinese Peoples Liberat Army Gen Hosp, Dept Neurol, Beijing 100853, Peoples R ChinaChinese Peoples Liberat Army Gen Hosp, Dept Neurol, Beijing 100853, Peoples R China