ORNITHINE ALPHA-KETOGLUTARATE IN NUTRITIONAL SUPPORT

被引：0
|
作者：
CYNOBER, L [1 ]
机构：
[1] UNIV PARIS 11,BIOCHIM LAB,F-92290 CHATENAY MALABRY,FRANCE
来源：
NUTRITION | 1991年 / 7卷 / 05期
关键词：
ORNITHINE; ALPHA-KETOGLUTARATE; GLUTAMINE; ARGININE; POLYAMINES; NUTRITIONAL SUPPORT;
D O I：
暂无
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Ornithine alpha-ketoglutarate (OKG) is a salt formed of two molecules of ornithine and one molecule of alpha-ketoglutarate. OKG has been successfully used by the enteral and parenteral route in bum, traumatized, and surgical patients and in chronically malnourished subjects. According to the metabolic situation, OKG treatment decreases muscle protein catabolism and/or increases synthesis. In addition, OKG promotes wound healing. The mechanism of action of OKG is not fully understood, but the secretion of anabolic hormones (insulin, human growth hormone) and the synthesis of metabolites (glutamine, polyamines, arginine, ketoacids) may be involved.
引用
收藏
页码：313 / 322
页数：10
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