MALIGNANT GERM-CELL TUMORS IN 2 SIBLINGS

被引：6
|
作者：
BLAKE, KI [1 ]
GERRARD, MP [1 ]
机构：
[1] CHILDRENS HOSP,DEPT PAEDIAT ONCOL,WESTERN BANK,SHEFFIELD S10 2TH,S YORKSHIRE,ENGLAND
来源：
MEDICAL AND PEDIATRIC ONCOLOGY | 1993年 / 21卷 / 04期
关键词：
FAMILIAL; GERM CELL TUMOR; OVARIAN; MALIGNANT;
D O I：
10.1002/mpo.2950210413
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Familial germ cell tumours are well recognised in kinship with gonadal dysgenesis, but their occurrence in siblings with normal chromosomes is rare. We report two sisters who presented within a 4 month period with malignant ovarian germ cell tumours; one a dysgerminoma and the other a mixed tumour with marked choriocarcinomatous elements. Both children had a normal female constitutional karyotype and normal phenotype.
引用
收藏
页码：299 / 300
页数：2
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